Since MDMA is both a stimulant and a hallucinogenic drug, the substance affects the body in two different ways. As a stimulant, MDMA affects dopamine levels in the brain, causing sensations such as increased alertness, attention, and energy. Once these stimulating effects go away, however, dopamine levels drop, causing people to experience a crash that’s known as a drug “comedown.”
As a hallucinogenic drug, MDMA activates certain serotonin receptors in the brain involved in emotions and sensory perception. When consumed, the substance primarily affects the cerebral cortex which helps regulate mood, cognition, and perception, as well as the locus coeruleus, which receives sensory signals. MDMA’s stimulating and hallucinogenic effects typically last anywhere from 3 to 6 hours.
These stimulating and hallucinogenic effects can also cause:
MDMA can also cause the body to overheat, which can lead to muscle breakdown, kidney, liver, and heart damage, and sometimes, death.
MDMA primarily affects the brain by increasing the activity of the body’s chemical messengers, including serotonin, dopamine, and norepinephrine. At first, this reaction signals the brain to produce euphoric feelings. But ultimately, this interaction causes the brain to identify MDMA as a primary source of these essential brain chemicals. When this happens, the brain stops producing serotonin, dopamine, and norepinephrine. This shutdown can cause neurotransmitter deficiencies. Even though the brain is arguably the body’s most complex organ, it relies on neurotransmitters and other chemicals to function properly.
Serotonin is a key player in regulating mood and behavior, but it also has an effect on many other bodily functions such as sleep, digestion, blood clotting, bone health, and sexual function. Low levels of serotonin can cause:
Dopamine, the “feel-good” chemical, helps regulate body movement, learning, memory, concentration, and mood. Dopamine also helps shape motivation. Low levels of the chemical messenger can cause:
Norepinephrine provides the body with energy and helps enhance focus levels. When the brain doesn’t produce enough norepinephrine, individuals can experience:
In addition to that, MDMA can:
Even though MDMA impacts everyone differently, some of the most common signs of MDMA use include:
Signs and symptoms of MDMA addiction include:
People exhibiting these signs may have an addiction to MDMA. If left untreated, an addiction to MDMA can cause:
All of these signs and symptoms point to an addiction to MDMA.